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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >    Cytokeratin 7 (KRT7) (Glandular and Transitional Epithelial Marker) Antibody   

Cytokeratin 7 (KRT7) (Glandular and Transitional Epithelial Marker) Antibody

Mouse Monoclonal Antibody [Clone K72.7 ]

  • IHC -  Cytokeratin 7 (KRT7) (Glandular and Transitional Epithelial Marker) Antibody AH11643
    Formalin-fixed, paraffin-embedded human Lung SCC stained with Cytokeratin 7 Monoclonal Antibody (K72.7)
  • IHC -  Cytokeratin 7 (KRT7) (Glandular and Transitional Epithelial Marker) Antibody AH11643
    Formalin-fixed, paraffin-embedded Ovarian Carcinoma stained with Cytokeratin 7 Monoclonal Antibody (K72.7)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P08729
Other Accession 3855, 411501
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names K72.7
Calculated MW 55kDa
Additional Information
Gene ID 3855
Other Names Keratin, type II cytoskeletal 7, Cytokeratin-7, CK-7, Keratin-7, K7, Sarcolectin, Type-II keratin Kb7, KRT7, SCL
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions Cytokeratin 7 (KRT7) (Glandular and Transitional Epithelial Marker) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT7
Synonyms SCL
Function Blocks interferon-dependent interphase and stimulates DNA synthesis in cells. Involved in the translational regulation of the human papillomavirus type 16 E7 mRNA (HPV16 E7).
Cellular Location Cytoplasm.
Tissue Location Expressed in cultured epidermal, bronchial and mesothelial cells but absent in colon, ectocervix and liver Observed throughout the glandular cells in the junction between stomach and esophagus but is absent in the esophagus
Research Areas
Citations (0)

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It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This MAb is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).


Ramaekers F, van Niekerk C, Poels L, Schaafsma E, Huijsmans A, Robben H, et al. Use of monoclonal antibodies to keratin 7 in the differential diagnosis of adenocarcinomas. Am J Pathol 1990;136:641-5

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$ 324.00
Cat# AH11643
(40 western blots)
Availability: 2-3 days
Bulk Size
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