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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >    Laminin, gamma 1 (LAMC1) Antibody - With BSA and Azide   

Laminin, gamma 1 (LAMC1) Antibody - With BSA and Azide

Rat Monoclonal Antibody [Clone A5 ]

  • IHC -  Laminin, gamma 1 (LAMC1) Antibody - With BSA and Azide AH11743
    Formalin-fixed, paraffin-embedded human Renal Cell Carcinoma stained with Laminin Monoclonal Antibody (A5).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P11047
Other Accession 3915, 609663, Q5VYE7, Q6NVY8
Reactivity Human, Mouse
Host Rat
Clonality Monoclonal
Isotype Rat / IgG2a, kappa
Clone Names A5
Calculated MW 210kDa
Additional Information
Gene ID 3915
Other Names Laminin subunit gamma-1, Laminin B2 chain, Laminin-1 subunit gamma, Laminin-10 subunit gamma, Laminin-11 subunit gamma, Laminin-2 subunit gamma, Laminin-3 subunit gamma, Laminin-4 subunit gamma, Laminin-6 subunit gamma, Laminin-7 subunit gamma, Laminin-8 subunit gamma, Laminin-9 subunit gamma, S-laminin subunit gamma, S-LAM gamma, LAMC1, LAMB2
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions Laminin, gamma 1 (LAMC1) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LAMC1
Synonyms LAMB2
Function Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
Cellular Location Secreted, extracellular space, extracellular matrix, basement membrane
Tissue Location Found in the basement membranes (major component)
Research Areas
Citations (0)

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Laminins are large hetero-trimeric, non-collagenous glycoproteins composed of α, β, and γ chains. This MAb reacts with laminin B2/1 chain of ~210kDa and does not cross-react with other basement membrane components or fibronectin. Its specificity was established by immunoprecipitation and immunofluorescence of human skeletal muscle and kidney with laminin chain-specific MAbs. Epithelial sheets in vivo are separated from the mesenchymal elements of the stroma by a thin layer of a specialized type of extracellular matrix termed the basement membrane (BM). This structure consists of individual components, some of which are ubiquitous in BMs and some are not. The ubiquitous ones comprise laminin (LN), entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms. This MAb stains uniformly all human and murine basement membranes.


Ljubimov AV et. al., Int J Cancer, 1992; 50:562-566. | Ljubimov AV et. al. Lab Investigation, 1995; 72:461-473. | Folkvord et. al., J Histochem Cytochem, 1989; 37:105-113

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$ 124.00
$ 324.00
$ 454.00
Cat# AH11743
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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