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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >    MUC2 (Mucin 2) Antibody   

MUC2 (Mucin 2) Antibody

Mouse Monoclonal Antibody [Clone CCP58 ]

  • IHC -  MUC2 (Mucin 2) Antibody AH11884
    Formalin-fixed, paraffin-embedded human Intestine stained with MUC2 Monoclonal Antibody (CCP58).
  • IHC -  MUC2 (Mucin 2) Antibody AH11884
    Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with MUC2 Monoclonal Antibody (CCP58).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q02817
Other Accession 4583, 315
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names CCP58
Calculated MW 520kDa
Additional Information
Gene ID 4583
Other Names Mucin-2, MUC-2, Intestinal mucin-2, MUC2, SMUC
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions MUC2 (Mucin 2) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MUC2
Synonyms SMUC
Function Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer.
Cellular Location Secreted. Note=In the intestine, secreted into the inner and outer mucus layers.
Tissue Location Colon, small intestine, colonic tumors, bronchus, cervix and gall bladder
Research Areas
Citations (0)

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Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as ĀGTQTP (GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.


Xing PX, Prenzoska J, Layton GT, Devine PL, McKenzie IF. Second-generation monoclonal antibodies to intestinal MUC2 peptide reactive with colon cancer. J Natl Cancer Inst. 1992; 84(9):699-703

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$ 324.00
Cat# AH11884
(40 western blots)
Availability: 2-3 days
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