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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >    NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) Antibody - Without BSA and Azide   

NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) Antibody - Without BSA and Azide

Mouse Monoclonal Antibody [Clone NTR/912 ]

  • IHC -  NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) Antibody - Without BSA and Azide AH12013
    Formalin-fixed, paraffin-embedded human Melanoma stained with NGFR Monoclonal Antibody (NTR/912).
  • IHC -  NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) Antibody - Without BSA and Azide AH12013
    Formalin-fixed, paraffin-embedded human Melanoma stained with NGFR Monoclonal Antibody (NTR/912).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P08138
Other Accession 4804, 415768, 681726
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names NTR/912
Calculated MW 75kDa
Additional Information
Gene ID 4804
Other Names Tumor necrosis factor receptor superfamily member 16, Gp80-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, NGF receptor, p75 ICD, CD271, NGFR, TNFRSF16
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms TNFRSF16
Function Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.


Soland, T.M., et al. 2008. Nerve growth factor receptor (p75NTR) and pattern of invasion predict poor prognosis in oral squamous cell carcinoma. Histopathology 53: 62-72. | Wang, W., et al. 2009. Patterns of expression and function of the p75NGFR protein in pancreatic cancer cells and tumours. Eur. J. Surg. Oncol. 35: 826-832. |

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$ 354.00
$ 484.00
Cat# AH12013
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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