PAX7 (Rhabdomyosarcoma Marker) Antibody - Without BSA and Azide
Mouse Monoclonal Antibody [Clone SPM613 ]
|Other Accession||5081, 113253|
|Isotype||Mouse / IgG1, kappa|
|Other Names||Paired box protein Pax-7, HuP1, PAX7, HUP1|
|Storage||Store at 2 to 8°C.Antibody is stable for 24 months.|
|Precautions||PAX7 (Rhabdomyosarcoma Marker) Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor playing a role in myogenesis through regulation of muscle precursor cells proliferation.|
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Provided below are standard protocols that you may find useful for product applications.
The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).
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