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GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Antibody - With BSA and Azide

Rat Monoclonal Antibody [Clone HSP90B1/1192 ]

  • IHC -  GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Antibody - With BSA and Azide AH12459
    Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with GRP94 Monoclonal Antibody (HSP90B1/1192).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P14625
Other Accession 7184, 192374
Reactivity Human
Host Rat
Clonality Monoclonal
Isotype Rat / IgG2a, kappa
Clone Names HSP90B1/1192
Calculated MW 94kDa
Additional Information
Gene ID 7184
Other Names Endoplasmin, 94 kDa glucose-regulated protein, GRP-94, Heat shock protein 90 kDa beta member 1, Tumor rejection antigen 1, gp96 homolog, HSP90B1, GRP94, TRA1
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HSP90B1
Synonyms GRP94, TRA1
Function Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity.
Cellular Location Endoplasmic reticulum lumen. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Research Areas
Citations (0)

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Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grp s are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.


Sorger, P.K. et al. J. Mol. Biol. 194: 341-344 (1987). | Tandon, A.K. Breast Cancer Res. and Treat. 16: 146 (1990). |

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$ 124.00
$ 324.00
$ 454.00
Cat# AH12459
(40 western blots)
Availability: 2-3 days
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