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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >    CD3 (T-Cell Marker) Antibody - Without BSA   

CD3 (T-Cell Marker) Antibody - Without BSA

Mouse Monoclonal Antibody [Clone B-B12 ]

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P07766
Other Accession 916, 3003
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names B-B12
Calculated MW 20kDa
Additional Information
Gene ID 916
Other Names T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T3E
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions CD3 (T-Cell Marker) Antibody - Without BSA is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD3E
Synonyms T3E
Function The CD3 complex mediates signal transduction.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Reacts with five invariable CD3 chains (designated as and ) with molecular weight ranging from 16-28kDa. CD3 is expressed, typically at high levels, on peripheral T cells and majority of T cell neoplasms. Thymocytes express CD3 at different level on the cell surface in the course of differentiation and, in cortical thymus, CD3 is predominantly Intracytoplasmic. The CD3 complex is closely associated at the lymphocyte cell surface with T cell antigen receptor (TCR) and is involved in transducing antigen-recognition signals into cytoplasm of T cells and in regulating the cell surface expression of the TCR complex.


Kishimoto T. et al., eds. Leukocyte Typing VI, p44-48 and p1111, Garland Publishing, Inc, New York and London, 1997.Meuer SC et al. Evidence for the T3-associated 90K heterodimer as the T-cell antigen receptor. Nature 1983, 303(5920):808-810 | Reinherz et al., Cell 30, 715, (1982) | Borst et al., J. Biol. Chem. 258, 5135, (1983) | Van den Elsen et al., Nature 312, (1984) | Furley et al., Cell 46, 75, (1986) | Gold et al., Nature 321, 4, (1986) | Oettgen and Terhorst, Hum. Immunol. 18, 187, (1987) | Clevers et al., Ann. Rev. Immunol. 6, 629, (1988

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$ 354.00
$ 484.00
Cat# AH12598
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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