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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >    CD5 (Mantle Cell Lymphoma Marker) Antibody - Without BSA and Azide   

CD5 (Mantle Cell Lymphoma Marker) Antibody - Without BSA and Azide

Mouse Monoclonal Antibody [Clone B-B8 ]

     
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  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IF, FC
Primary Accession P06127
Other Accession 921, 58685
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names B-B8
Calculated MW 67kDa
Additional Information
Gene ID 921
Other Names T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1, CD5, CD5, LEU1
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions CD5 (Mantle Cell Lymphoma Marker) Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD5
Synonyms LEU1
Function May act as a receptor in regulating T-cell proliferation.
Cellular Location Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Background

Recognizes a 67kDa transmembrane protein which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Note that this MAb is not suitable for frozen tissues.

References

Berezowski K; et al. American Journal of Clinical Pathology, 1996 Oct, 106(4):483-6. | Ferry JA; et al. American Journal of Clinical Pathology, 1996 Jan, 105(1):31-7

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$ 354.00
$ 484.00
Cat# AH12616
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