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CD6 Antibody

Mouse Monoclonal Antibody [Clone SPM547 ]

  • IHC -  CD6 Antibody AH12619
    Formalin-fixed, paraffin-embedded human Tonsil stained with CD6 Monoclonal Antibody (SPM547).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P30203
Other Accession 923, 744366
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1
Clone Names SPM547
Calculated MW 90-130kDa
Additional Information
Gene ID 923
Other Names T-cell differentiation antigen CD6, T12, TP120, CD6, CD6
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions CD6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD6
Function Involved in cell adhesion. Binds to CD166.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain
Research Areas
Citations (0)

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CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular �scavenger receptor cysteine-rich� (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.


Bazil, V et. al. 1989. Monoclonal antibodies against human leucocyte antigens. III. Antibodies against CD45R, CD6, CD44 and two newly described broadly expressed glycoproteins MEM-53 and MEM-102. Folia. Biol. 35:289-297

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$ 324.00
Cat# AH12619
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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