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CD20 / MS4A1 (B-Cell Marker) Antibody

Mouse Monoclonal Antibody [Clone SPM494 ]

  • IHC -  CD20 / MS4A1 (B-Cell Marker) Antibody AH12660
    Formalin-fixed, paraffin-embedded human Lymphoma stained with CD20 Monoclonal Antibody (SPM494)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P11836
Other Accession 931, 712553
Reactivity Human, Monkey, Baboon
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG2a, kappa
Clone Names SPM494
Calculated MW 33-37kDa
Additional Information
Gene ID 931
Other Names B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD20, MS4A1, CD20
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions CD20 / MS4A1 (B-Cell Marker) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MS4A1
Synonyms CD20
Function This protein may be involved in the regulation of B-cell activation and proliferation.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor
Tissue Location Expressed on B-cells.
Research Areas
Citations (0)

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Recognizes a protein of 30-33kDa, which is identified as CD20. Its epitope is located in the cytoplasmic domain of CD20 and was, therefore, ascribed as CD20cy in the 5th Workshop. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin s disease, particularly of lymphocyte predominant type.


Schlossman, S., et al., eds. 1995. Leucocyte Typing V. New York: Oxford University Press. |

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$ 324.00
Cat# AH12660
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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