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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >    CD20 / MS4A1 (B-Cell Marker) Antibody - With BSA and Azide   

CD20 / MS4A1 (B-Cell Marker) Antibody - With BSA and Azide

Mouse Monoclonal Antibody [Clone 109-3C2 ]

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P11836
Other Accession 931, 712553
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG3, kappa
Clone Names 109-3C2
Calculated MW 33-37kDa
Additional Information
Gene ID 931
Other Names B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD20, MS4A1, CD20
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions CD20 / MS4A1 (B-Cell Marker) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MS4A1
Synonyms CD20
Function This protein may be involved in the regulation of B-cell activation and proliferation.
Cellular Location Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor
Tissue Location Expressed on B-cells.
Research Areas
Citations (0)

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Recognizes a protein of 30-33kDa, which is identified as CD20 (Workshop V; Code CD20.12. Workshop IV; Code B17). It recognizes an extracellular domain of CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. The protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B-cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as calcium channel involved in B cell activation and cell cycle progression.


Schlossman S, et al. (eds). Leukocyte Typing V, Oxford University Press, Oxford, p511-515, 1995. | Knapp W et al. (eds) Leukocytes Typing IV, Oxford University Press, Oxford, p51, 1989. | Tedder TF and Schlossman SF. Phosphorylation of the B1 (CD20) molecule by normal and malignant human B-lymphocytes. J Biol Chem 1988, 263(20):10009-10015. | Bubien JK et al. Transfection of the CD20 cell surface molecule into ectopic cell types generates a Ca2+ conductance found constitutively in B-lymphocytes. J Cell Biol 1993, 121(5):1121-1132. | Tedder TF and Engel P. CD20: a regulator of cell-cycle progression of B-lymphocytes. Immunol Today 1994, 15(9):450-454. | Kanzaki M et al. Expression of calcium-permeable cation channel CD20 accelerates progression through the G1 phase in Balb/c 3T3 cells. J Biol Chem 1995, 270(22):13099-13104

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$ 124.00
$ 324.00
$ 454.00
Cat# AH12671
(40 western blots)
Availability: 2-3 days
Bulk Size
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