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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >    CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Antibody   

CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Antibody

Mouse Monoclonal Antibody [Clone SPM609 ]

  • IHC -  CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Antibody AH12694
    Formalin-fixed, paraffin-embedded human Hodgkin's Lymphoma stained with CD30 Monoclonal Antibody (SPM609).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P28908
Other Accession 943, 1314
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names SPM609
Calculated MW 105-120kDa
Additional Information
Gene ID 943
Other Names Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30, CD30, TNFRSF8, CD30, D1S166E
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CD30, D1S166E
Function Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF- kappa-B.
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This MAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).


Smith, C.A., et al. 1993. CD30 antigen, a marker for Hodgkin s lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF. Cell 73: 1349-1360. |

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$ 324.00
Cat# AH12694
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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