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Napsin A (Lung Adenocarcinoma Marker) Antibody - With BSA and Azide

Mouse Monoclonal Antibody [Clone NAPSA/1238 + NAPSA/1239 ]

     
  • IHC -  Napsin A (Lung Adenocarcinoma Marker) Antibody - With BSA and Azide AH12720-20
    Formalin-fixed, paraffin-embedded human Lung Adenocarcinoma stained with Napsin-A Monoclonal Antibody (NAPSA/1238 + NAPSA/1239).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF, FC
Primary Accession O96009
Other Accession 9476, 512843
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG, kappa
Clone Names NAPSA/1238 + NAPSA/1239
Calculated MW 37kDa
Additional Information
Gene ID 9476
Other Names Napsin-A, 3.4.23.-, Aspartyl protease 4, ASP4, Asp 4, Napsin-1, TA01/TA02, NAPSA, NAP1, NAPA
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions Napsin A (Lung Adenocarcinoma Marker) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NAPSA
Synonyms NAP1, NAPA
Function May be involved in processing of pneumocyte surfactant precursors.
Cellular Location Secreted.
Tissue Location Expressed predominantly in adult lung (type II pneumocytes) and kidney and in fetal lung. Low levels in adult spleen and very low levels in peripheral blood leukocytes
Research Areas
Citations (0)
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Background

Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B.ĀThere are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.

References

Bishop, JA et. al. Hum Pathol 41: 20-25 | Ordonez, NG 2012 Adv Anat Pathol 19: 66-73 | Ye, J et. al. Appl Immunhistochem Mol Morphol 19: 313-31

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$ 219.00
$ 499.00
Cat# AH12720-20
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