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>   home   >   Products   >   Primary Antibodies   >   Immunology   >    CD37 (Peripheral Mature B-Cell Marker) Antibody - Without BSA and Azide   

CD37 (Peripheral Mature B-Cell Marker) Antibody - Without BSA and Azide

Mouse Monoclonal Antibody [Clone IPO-24 ]

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P11049
Other Accession 951, 166556
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG2b, kappa
Clone Names IPO-24
Calculated MW 33-55kDa
Additional Information
Gene ID 951
Other Names Leukocyte antigen CD37, Tetraspanin-26, Tspan-26, CD37, CD37, TSPAN26
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions CD37 (Peripheral Mature B-Cell Marker) Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD37
Synonyms TSPAN26
Cellular Location Membrane; Multi-pass membrane protein.
Tissue Location B-lymphocytes.
Research Areas
Citations (0)

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Recognizes a protein of 33-55kDa, identified as CD37 (Workshop V; Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'ā€™ lymphoma (B-NHL).


Schlossman SF et al. eds. Leukocyte Typing V, p556-559, Oxford University Press, Oxford, 1995. | Sidorenko SP et al. Monoclonal antibodies of the IPO series in studying and diagnosing malignant lymphoproliferative diseases. Gematol Transfuziol 1990, 35(4):19-22 | Sidorenko SP et al. Monoclonal antibodies of IPO series against B cell differentiation antigens in leukemia and lymphoma immunophenotyping Neoplasma 1992;39(1):3-9. | Maecker HT et al. The tetraspanin superfamily: molecular facilitators. FASEB J 1997,11(6):428-442 | Angelisova P et al. Association of four antigens of the tetraspans family (CD37, CD53, TAPA-1, and R2/C33) with MHC class II glycoproteins. Immunogenetics 1994;39(4):249-256

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$ 354.00
$ 484.00
Cat# AH12731
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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