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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >    CD70 / TNFSF7 (Activated T- & B-Lymphocyte Marker) Antibody - Without BSA and Azide   

CD70 / TNFSF7 (Activated T- & B-Lymphocyte Marker) Antibody - Without BSA and Azide

Mouse Monoclonal Antibody [Clone BU69 ]

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P32970
Other Accession 970, 501497, 715224
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names BU69
Calculated MW 30kDa
Additional Information
Gene ID 970
Other Names CD70 antigen, CD27 ligand, CD27-L, Tumor necrosis factor ligand superfamily member 7, CD70, CD70, CD27L, CD27LG, TNFSF7
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions CD70 / TNFSF7 (Activated T- & B-Lymphocyte Marker) Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD70
Synonyms CD27L, CD27LG, TNFSF7
Function Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
Cellular Location Membrane; Single-pass type II membrane protein
Research Areas
Citations (0)

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It recognizes a protein of 30kDa, identified as CD70. It is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and B-lymphocytes. It induces proliferation of co-stimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. This MAb blocks the interaction between CD27 and CD70, and has been shown toĀinhibit T cell proliferation induced by dendritic cells.


R.Q. Hintzen, et al, (1994) J Immunol 152: 1762-1773. | M.R. Bowman, et al, (1994) J Immunol 152: 1756-1761. | Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1137-1138. | K. Agematsu, et al, (1995) J Immunol 154: 3627-3635

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$ 354.00
$ 484.00
Cat# AH12801
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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