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>   home   >   Products   >   Primary Antibodies   >    Lewis A (Blood Group Antigen) Antibody   

Lewis A (Blood Group Antigen) Antibody

Mouse Monoclonal Antibody [Clone 7LE ]

     
  • IHC -  Lewis A (Blood Group Antigen) Antibody AH12864-7
    Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with Lewis A Monoclonal Antibody (7LE).
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC, IF, FC
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names 7LE
Calculated MW Multiple KDa
Additional Information
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions Lewis A (Blood Group Antigen) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Citations (0)

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Background

Recognizes a carbohydrate determinant of Gal 1-3(Fuc 1-4) GlcNAc which is blood group antigen Lewis A. It is present primarily on epithelial cells such as colon and kidneys. In the tumors and dedifferentiated tissues, decrease of Lewis A antigen was observed. Lewis A (type 1 chain) is expressed in colonic epithelial cells and may be useful for detection of gastrointestinal tumors, pancreatic cancer, and colorectal tumors. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

References

Blood transfusion and immunohaematology, Ph. Rouger, D Anstee and Ch. Salmon (Eds). Arnette, France 30 (5): 353-720 (1987). | Cancer Epidemiology, Biomarkers Prevention 1, 199-205 (1992). | Gastroenterology, 102 (2), 424-430 (1992)

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$ 324.00
Cat# AH12864-7
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