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>   home   >   Products   >   Primary Antibodies   >    PNL2 (Melanoma Associated Antigen) Antibody - Without BSA and Azide   

PNL2 (Melanoma Associated Antigen) Antibody - Without BSA and Azide

Mouse Monoclonal Antibody [Clone PNL2 ]

  • IHC -  PNL2 (Melanoma Associated Antigen) Antibody - Without BSA and Azide AH12893
    Formalin-fixed, paraffin-embedded human Melanoma stained with PNL2 Monoclonal Antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Reactivity Human, Mouse, Drosophila
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1
Clone Names PNL2
Calculated MW Multiple (160kDa, 100kDa and <10kDa)
Additional Information
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions PNL2 (Melanoma Associated Antigen) Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Citations (0)

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Anti-PNL2 is a novel monoclonal antibody, which has recently been introduced as an immunohistochemical reagent to stain melanocytes and tumors derived therefrom. The antigen recognized by PNL2 is different from Melan A and gp100. Its epitope is not destroyed by digestion with neuraminidase i.e. its epitope id not glycosylated. Anti-PNL2 may be most useful because of its high sensitivity for metastatic melanoma (87%), as opposed to 76% for anti-HMB45 and 82% for anti-MART-1. Anti-PNL2 labels intra-epidermal nevi while the dermal component of compound nevi are largely non-reactive with anti-PNL2. Antibodies against PNL2, MART-1 (Melan A) and HMB45 stain most clear cell sarcoma cells and a few cells in angio-myolipomas and lymphangioleiomyomatosis. Anti-PNL2 is a useful antibody for the identification of melanomas and clear cell sarcomas. Differential diagnosis is aided by the results from a panel of antibodies, including antibodies against HMB45, MART-1, tyrosinase, and MiTF.


Rochaix, P et al. PNL2, a New Monoclonal Antibody Directed against a Fixative-Resistant Melanocyte Antigen. Mod Pathol 2003;16(5):481-490. | J. A. Ramos-Vara and M. A. Miller. Immunohistochemical Identification of Canine Melanocytic Neoplasms With Antibodies to Melanocytic Antigen PNL2 and Tyrosinase: Comparison With Melan A. Veterinary Pathology OnlineFirst, published on September 21, 2010 as doi:10.1177/0300985810382095

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$ 354.00
$ 484.00
Cat# AH12893
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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