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Cytokeratin, pan (Epithelial Marker) Antibody - With BSA and Azide

Mouse Monoclonal Antibody [Clone PAN-CK (Cocktail) ]

     
  • IHC -  Cytokeratin, pan (Epithelial Marker) Antibody - With BSA and Azide AH12926-20
    Formalin-fixed, paraffin-embedded human Skin stained with Cytokeratin, pan Monoclonal Antibody cocktail (PAN-CK).
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF, FC
Primary Accession Q7Z794
Other Accession 374454 (KRT77), 51350 (KRT76), 334989 (KRT77), 654392 (KRT76), Q01546 (KRT76)
Reactivity Human, Mouse, Rat, Rabbit, Monkey, Chicken, Cow, Dog
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG’s, kappa
Clone Names PAN-CK (Cocktail)
Calculated MW 40-67kDa (Multiple)
Additional Information
Gene ID 374454
Other Names Keratin, type II cytoskeletal 1b, Cytokeratin-1B, CK-1B, Keratin-77, K77, Type-II keratin Kb39, KRT77, KRT1B
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions Cytokeratin, pan (Epithelial Marker) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT77
Synonyms KRT1B
Tissue Location Expressed exclusively in skin.
Research Areas
Citations (0)
citation

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Background

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI 6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, with 67kDa (CK1); 64kDa (CK3); 59kDa (CK4); 58kDa (CK5); 56kDa (CK6); 55kDa (CK7); 52kDa (CK8); 56.5kDa (CK10); 53kDa (CK13); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 46kDa (CK17); 45kDa (CK18) and 40kDa (CK19). Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. KRT-PAN is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It is useful in characterizing the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and shows high sensitivity in the recognition of epithelial cells and carcinomas.

References

Woodock-Mitchell J et. al. Journal of Cell Biology 1982;95:580-8. | Tseng SCG et. al. Cell 1982; 30361

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$ 219.00
$ 499.00
Cat# AH12926-20
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