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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >    Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Antibody   

Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Antibody

Mouse Monoclonal Antibody [Clone 34BE12 ]

     
  • IHC -  Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Antibody AH13015
    Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with Cytokeratin, HMW Monoclonal Antibody (34BE12).
  • IHC -  Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Antibody AH13015
    Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with Cytokeratin, HMW Monoclonal Antibody (34BE12).
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF, FC
Primary Accession Q01546
Other Accession 51350, 654392
Reactivity Human, Mouse, Rat
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG1, kappa
Clone Names 34BE12
Calculated MW 50-67kDa
Additional Information
Gene ID 51350
Other Names Keratin, type II cytoskeletal 2 oral, Cytokeratin-2P, CK-2P, K2P, Keratin-76, K76, Type-II keratin Kb9, KRT76, KRT2B, KRT2P
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions Cytokeratin, Basic (Type II or HMW) (Epithelial Marker) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT76
Synonyms KRT2B, KRT2P
Function Probably contributes to terminal cornification.
Research Areas
Citations (0)

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Background

This antibody recognizes CK1, CK5, CK10 and CK14. In normal epithelia, it stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. This MAb shows no reactivity with hepatocytes, pancreatic acinar cells, proximal renal tubules, or endometrial glands; there is no reactivity with cells derived from simple epithelia. Mesenchymal tumors, lymphomas, melanomas, neural tumors, and neuroendocrine tumors are negative with this antibody. It stains myoepithelial cells and has been shown to be useful in distinguishing prostate adenocarcinoma from benign prostate. This antibody has also been useful in separating benign from malignant intraductal breast proliferations.

References

Moinfar F et. al. Am J Surg Pathol 1999;23(9):1048-58 | Varma M et. al. Mod Pathol 1999;12(5):472-8 |

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$ 324.00
Cat# AH13015
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