|Application ||IHC-P, IF|
|Isotype||Mouse / IgG1|
|Calculated MW||Not Known KDa|
|Storage||Store at 2 to 8°C.Antibody is stable for 24 months.|
|Precautions||HepPar-1 (Hepatocellular Marker) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
Hepatocyte Paraffin 1 or HepPar1 localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. The Hepatocyte Specific Antigen may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of the Hepatocyte Specific Antigen correlates with smaller tumor size and longer patient survival. Occasionally, Hepatocyte Specific Antigen is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Wennerberg AE et. al. Am J Pathol 1993;143:1050-4. Ramos-Vara, J.A., et al. Histochem 2002; J. 34: 397-401.Fan, Z., et al. Mod. Pathol 2003; 16: 137-144, 2003
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