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Bromodeoxyuridine (BrdU) (Proliferation Marker) Antibody - With BSA and Azide
Mouse Monoclonal Antibody [Clone 85-2C8 ]
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, IF, FC |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | Mouse / IgG1 |
| Clone Names | 85-2C8 |
| Calculated MW | Depends on the target KDa |
| Storage | Store at 2 to 8°C.Antibody is stable for 24 months. |
|---|---|
| Precautions | Bromodeoxyuridine (BrdU) (Proliferation Marker) Antibody - With BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
It reacts with Bromodeoxyuridine (BrdU) in single stranded DNA (produced by partial denaturation of double stranded DNA), BrdU coupled to a protein carrier, as well as free BrdU. BrdU is a thymidine analog, incorporated into cell nuclei during DNA synthesis prior to mitosis. Antibody to BrdU is helpful in detecting S-phase cells, providing useful information on the aggressiveness of tumors.
References
Acta Histochemica, Supplement. Band XXXVI. 353–359 (1988). | Raza A, Ucar K and Preisler H D. Cytometry. 6: 633–640 (1985). | Raza A, Preisler H D, Mayers G L, et al.. New England Journal of Medicine. 310 (15): 991 (1984). | Gratzner H G. Science. 218: 474–475 (1982)
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