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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >    Cytokeratin 8/18 Antibody - Without BSA and Azide   

Cytokeratin 8/18 Antibody - Without BSA and Azide

Mouse Monoclonal Antibody [Clone C-43 + DC10 ]

  • IHC -  Cytokeratin 8/18 Antibody - Without BSA and Azide AH13056
    Formalin-fixed, paraffin-embedded human Lung Carcinoma stained with Cytokeratin 8/18 Monoclonal Antibody (C-43 + DC10).
  • IHC -  Cytokeratin 8/18 Antibody - Without BSA and Azide AH13056
    Formalin-fixed, paraffin-embedded human Ovarian Cancer stained with Cytokeratin 8/18 Monoclonal Antibody (C-43 + DC10).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05787
Other Accession 3856 (CK8), 3875 (CK18), 533782, 708445 (CK8), 406013 (CK18), P05783 (CK18)
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG's
Clone Names C-43 + DC10
Calculated MW 52.5kDa (CK8); 45kDa (CK18)
Additional Information
Gene ID 3856
Other Names Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8, KRT8, CYK8
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
Precautions Cytokeratin 8/18 Antibody - Without BSA and Azide is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT8
Synonyms CYK8
Function Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
Cellular Location Cytoplasm. Nucleus, nucleoplasm Nucleus matrix
Tissue Location Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity.
Research Areas
Citations (0)

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Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.ĀImmunohistochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.


Angus B et. al. J Path, 153:377-384, 1987. | Angus B et. al. J Path, 155:71-75, 1988 |

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$ 354.00
$ 484.00
Cat# AH13056
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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