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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Ksp-Cadherin / CDH16 Antibody   

Anti-Ksp-Cadherin / CDH16 Antibody

Recombinant Rabbit Monoclonal Antibody

     
  • IHC-P - Anti-Ksp-Cadherin / CDH16 Antibody AH13079-20
    Formalin-fixed, paraffin-embedded Human Renal Cell Carcinoma Stained with KSP-Cadherin Recombinant Rabbit Monoclonal Antibody (CDH16/1532R)
  • IHC-P - Anti-Ksp-Cadherin / CDH16 Antibody AH13079-20
    Formalin-fixed, paraffin-embedded Rat Kidney stained with KSP-Cadherin Recombinant Rabbit Monoclonal Antibody (CDH16/1532R)
  • IHC-P - Anti-Ksp-Cadherin / CDH16 Antibody AH13079-20
    Formalin-fixed, paraffin-embedded Mouse Kidney Stained with KSP-Cadherin Rabbit Monoclonal Antibody (CDH16/1532R)
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, IF, FC
Primary Accession O75309
Other Accession 513660
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal
Isotype Rabbit / IgG, kappa
Clone Names CDH16/1532R
Calculated MW 89923 Da
Additional Information
Gene ID 1014
Other Names Cadherin-16 (CDH16); Kidney-specific cadherin; Ksp-cadherin antibody
Application Note Flow Cytometry (0.5-1ug/million cells); Immunofluorescence (1-2ug/ml); ,Immunohistology (Formalin-fixed) (0.5-1ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA buffer, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Format 200ug/ml of Ab purified by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
PrecautionsAnti-Ksp-Cadherin / CDH16 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDH16
Function Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Kidney specific.
Research Areas
Citations (0)

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Background

This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels. Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

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$ 199.00
$ 429.00
Cat# AH13079-20
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