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Anti-Adipophilin / Perilipin-2 (Marker of Obesity) Antibody

Mouse Monoclonal Antibody

     
  • IHC-P - Anti-Adipophilin / Perilipin-2 (Marker of Obesity) Antibody AH13125-20
    Formalin-fixed, paraffin-embedded human Adrenal stained with Adipophilin Monoclonal Antibody (ADFP/1366).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, IF, E
Primary Accession Q99541
Other Accession 3416
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgG2b, kappa
Clone Names ADFP/1366
Calculated MW 48075 Da
Additional Information
Gene ID 123
Other Names Adipophilin; ADFP; Adipose differentiation-related protein (ADRP); Perilipin-2 (PLIN2)
Application Note ELISA (For coating, order Ab without BSA);,Immunofluorescence (0.5-1ug/ml); ,Immunohistology (Formalin-fixed) (0.5-1.0ug/ml for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Format 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
PrecautionsAnti-Adipophilin / Perilipin-2 (Marker of Obesity) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLIN2
Synonyms ADFP
Function May be involved in development and maintenance of adipose tissue.
Cellular Location Membrane; Peripheral membrane protein. Lipid droplet
Tissue Location Milk lipid globules.
Research Areas
Citations (0)

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Background

Recognizes a protein of 48kDa, which is identified as Adipophilin. It belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases.

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$ 199.00
$ 429.00
Cat# AH13125-20
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