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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Lewis Y (Tumor Marker) Antibody   

Anti-Lewis Y (Tumor Marker) Antibody

Mouse Monoclonal Antibody

     
  • IHC-P - Anti-Lewis Y (Tumor Marker) Antibody AH13664-20
    Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with Lewis Y Monoclonal Antibody (A70-C/C8).
  • IHC-P - Anti-Lewis Y (Tumor Marker) Antibody AH13664-20
    Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with Lewis Y Monoclonal Antibody (A70-C/C8).
  • IHC-P - Anti-Lewis Y (Tumor Marker) Antibody AH13664-20
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, IF, FC
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype Mouse / IgM
Clone Names A70-C/C8
Additional Information
Other Names Lewis Y antigen
Application Note Flow Cytometry (0.5-1ug/million cells); ,Immunofluorescence (0.5-1ug/ml); ,Immunohistology (Formalin-fixed) (0.5-1.0ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Format 200ug/ml of Ab purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
StorageStore at 2 to 8°C.Antibody is stable for 24 months.
PrecautionsAnti-Lewis Y (Tumor Marker) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Research Areas
Citations (0)

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Background

This antibody recognizes a carbohydrate epitope common to the tumor-associated Lewis Y and Lewis b antigens (Fucalpha1-2Galbeta1-4/3[Fucalpha1-3/4]GlcNAcbeta-). Its specificity was established without doubt with a panel of 86 synthetic mono- and oligosaccharidic structures. Lewis Y is expressed in large bowel tumors and colorectal carcinomas. It may be useful in the classification of human renal and bladder tumors. The Lewis Y antigen has been evaluated as a clinical marker for the diagnosis and prognosis of cholangiocarcinoma, hepatocellular carcinoma and breast cancer.

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$ 199.00
$ 429.00
Cat# AH13664-20
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