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DYRK3 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • IF - DYRK3 antibody - N-terminal region AI10011
    DYRK3 antibody - N-terminal region (AI10011) in HeLas cells using Immunofluorescence
    Sample Type : HeLa cells

    Primary Antibody Dilution : 1:50

    Secondary Antibody : Gaot anti-rabbit-Alexa Fluor
    Secondary Antibody Dilution : 1:250
    Color/Signal Descriptions : Green: DYRK3Red: PABP1Blue: DAPI

    Gene Name : DYRK3
    Submitted by : Frank Wippich, Institute of Molecular Life Sciences, University of Zurich
  • WB - DYRK3 antibody - N-terminal region AI10011
    DYRK3 antibody - N-terminal region (AI10011) in Human THP-1 cells using Western Blot
    WB Suggested Anti-DYRK3 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:312500
    Positive Control: THP-1 cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43781
Other Accession O43781, NP_003573, NM_003582
Reactivity Human, Mouse
Predicted Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 66 kDa
Additional Information
Gene ID 8444
Alias Symbol DYRK5, RED, REDK, hYAK3-2
Other Names Dual specificity tyrosine-phosphorylation-regulated kinase 3, Regulatory erythroid kinase, REDK, DYRK3
Target/Specificity This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified.
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-DYRK3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsDYRK3 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DYRK3
Function Negative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling.
Cellular Location Nucleus.
Tissue Location Isoform 1 and isoform 2 are highly expressed in testis and in hematopoietic tissue such as fetal liver, and bone marrow. Isoform 2 is the predominant form in testis. Isoform 1 is the predominant form in fetal liver and bone marrow. Isoform 1 and isoform 2 are present at low levels in heart, pancreas, lymph node, and thymus.
Research Areas
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This is a rabbit polyclonal antibody against DYRK3. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (

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$ 293.00
Cat# AI10011
(40 western blots)
Availability: 2-3 days
Bulk Size
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