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HHEX antibody - middle region

Rabbit Polyclonal Antibody

     
  • IHC - HHEX antibody - middle region AI10016
    HHEX antibody - middle region (AI10016) in Human Muscle cells using Immunohistochemistry
    HumanMuscle
    detail
  • IHC - HHEX antibody - middle region AI10016
    Human Lung
    Rabbit Anti-HHEX Antibody
    Paraffin Embedded Tissue: Human alveolar cell
    Cellular Data: Epithelial cells of renal tubule
    Antibody Concentration: 4.0-8.0 μg/ml
    Magnification: 400X
    detail
  • WB - HHEX antibody - middle region AI10016
    HHEX antibody - middle region (AI10016) in Human K562 cells using Western Blot
    WB Suggested Anti-HHEX Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:312500
    Positive Control: K562 cell lysate
    HHEX is strongly supported by BioGPS gene expression data to be expressed in Human K562 cells
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession Q03014
Other Accession Q03014, NP_002720, NM_002729
Reactivity Human, Mouse, Rat, Pig, Dog, Guinea Pig, Horse, Bovine
Predicted Human, Mouse, Rat, Pig, Dog, Guinea Pig, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 30 kDa
Additional Information
Gene ID 3087
Alias Symbol HEX, PRH, HMPH, PRHX, HOX11L-PEN
Other Names Hematopoietically-expressed homeobox protein HHEX, Homeobox protein HEX, Homeobox protein PRH, HHEX, HEX, PRH, PRHX
Target/Specificity HHEX encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation.
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-HHEX antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsHHEX antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HHEX
Synonyms HEX, PRH, PRHX
Function Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor (By similarity). Activator of WNT-mediated transcription in conjunction with CTNNB1 (PubMed:20028982). Establishes anterior identity at two levels; acts early to enhance canonical WNT- signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL (By similarity). Inhibits EIF4E-mediated mRNA nuclear export (PubMed:12554669). May play a role in hematopoietic differentiation (PubMed:8096636).
Cellular Location Nucleus {ECO:0000250|UniProtKB:P43120}. Nucleus, nuclear body. Cytoplasm
Tissue Location Liver and promyelocytic leukemia cell line HL-60.
Research Areas
Citations (0)
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Background

This is a rabbit polyclonal antibody against HHEX. It was validated on Western Blot and immunohistochemistry by Abgent. At Abgent we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high throughput manner. Our antibodies are peptide based and protein family oriented. We usually provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).

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$ 389.00
Cat# AI10016
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