HHEX antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
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Primary Accession | Q03014 |
Other Accession | Q03014, NP_002720, NM_002729 |
Reactivity | Human, Mouse, Rat, Pig, Dog, Guinea Pig, Horse, Bovine |
Predicted | Human, Mouse, Rat, Pig, Dog, Guinea Pig, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 30 kDa |
Gene ID | 3087 |
---|---|
Alias Symbol | HEX, PRH, HMPH, PRHX, HOX11L-PEN |
Other Names | Hematopoietically-expressed homeobox protein HHEX, Homeobox protein HEX, Homeobox protein PRH, HHEX, HEX, PRH, PRHX |
Target/Specificity | HHEX encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation. |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-HHEX antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
Precautions | HHEX antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | HHEX |
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Synonyms | HEX, PRH, PRHX |
Function | Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor (By similarity). Activator of WNT-mediated transcription in conjunction with CTNNB1 (PubMed:20028982). Establishes anterior identity at two levels; acts early to enhance canonical WNT- signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL (By similarity). Inhibits EIF4E-mediated mRNA nuclear export (PubMed:12554669). May play a role in hematopoietic differentiation (PubMed:8096636). |
Cellular Location | Nucleus {ECO:0000250|UniProtKB:P43120}. Nucleus, nuclear body. Cytoplasm |
Tissue Location | Liver and promyelocytic leukemia cell line HL-60. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This is a rabbit polyclonal antibody against HHEX. It was validated on Western Blot and immunohistochemistry by Abgent. At Abgent we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high throughput manner. Our antibodies are peptide based and protein family oriented. We usually provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).
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