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>   home   >   Products   >   Primary Antibodies   >   ZNF274 antibody - N-terminal region   

ZNF274 antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • IHC - ZNF274 antibody - N-terminal region AI10020
    ZNF274 antibody - N-terminal region (AI10020) in Human Heart cells using Immunohistochemistry
    Human Heart
  • IHC - ZNF274 antibody - N-terminal region AI10020
    ZNF274 antibody - N-terminal region (AI10020) in Human kidney cells using Immunohistochemistry
    Human kidney
  • WB - ZNF274 antibody - N-terminal region AI10020
    ZNF274 antibody - N-terminal region (AI10020) in Human Jurkat cells using Western Blot
    WB Suggested Anti-ZNF274 Antibody Titration: 2.5μg/ml
    ELISA Titer: 1:312500
    Positive Control: Jurkat cell lysate
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession Q96GC6
Other Accession Q96GC6-3, NP_057408, NM_016324
Reactivity Human, Mouse, Rat, Rabbit, Pig, Dog, Bovine
Predicted Rabbit, Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 62 kDa
Additional Information
Gene ID 10782
Alias Symbol DKFZp686K08243, HFB101, ZF2, ZKSCAN19
Other Names Neurotrophin receptor-interacting factor homolog, Zinc finger protein 274, Zinc finger protein HFB101, Zinc finger protein with KRAB and SCAN domains 19, Zinc finger protein zfp2, Zf2, ZNF274, ZKSCAN19
Target/Specificity ZNF274 is a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus.This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals.
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-ZNF274 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsZNF274 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZNF274
Synonyms ZKSCAN19
Function Probable transcription repressor. Specifically binds to the 3'-end of zinc-finger coding genes and recruiting chromatin- modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression. The SETDB1-TRIM28-ZNF274 complex may play a role in recruiting ATRX to the 3'-exons of zinc-finger coding genes with atypical chromatin signatures to establish or maintain/protect H3K9me3 at these transcriptionally active regions (PubMed:27029610).
Cellular Location Cytoplasm. Nucleus, nucleolus
Citations (0)

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Background

This is a rabbit polyclonal antibody against ZNF274. It was validated on Western Blot and immunohistochemistry by Abgent. At Abgent we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high throughput manner. Our antibodies are peptide based and protein family oriented. We usually provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).

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$ 232.00
Cat# AI10020
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