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TNRC4 antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - TNRC4 antibody - N-terminal region AI10022
    TNRC4 antibody - N-terminal region (AI10022) in Human Jurkat cells using Western Blot
    WB Suggested Anti-TNRC4 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:1562500
    Positive Control: Jurkat cell lysate
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q5SZQ8
Other Accession Q5SZQ8, NP_009116, NM_007185
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 51 kDa
Additional Information
Gene ID 11189
Alias Symbol BRUNOL1, CAGH4, CELF3, ERDA4, MGC57297, TNRC4
Other Names CUGBP Elav-like family member 3, CELF-3, Bruno-like protein 1, CAG repeat protein 4, CUG-BP- and ETR-3-like factor 3, ELAV-type RNA-binding protein 1, ETR-1, Expanded repeat domain protein CAG/CTG 4, RNA-binding protein BRUNOL-1, Trinucleotide repeat-containing gene 4 protein, CELF3, BRUNOL1, CAGH4, ERDA4, TNRC4
Target/Specificity Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation.Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. While several transcript variants may exist for this gene, the full-length nature of only one has been biologically validated to date.
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-TNRC4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsTNRC4 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CELF3
Synonyms BRUNOL1, CAGH4, ERDA4, TNRC4
Function RNA-binding protein involved in the regulation of pre- mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
Cellular Location Nucleus. Cytoplasm
Tissue Location Expressed in brain.
Research Areas
Citations (0)

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Background

This is a rabbit polyclonal antibody against TNRC4. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).

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$ 293.00
Cat# AI10022
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