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SCMH1 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q96GD3 |
| Other Accession | Q96GD3-4, NP_036368, NM_012236 |
| Reactivity | Human, Mouse, Rat, Rabbit, Dog, Horse, Bovine, Yeast |
| Predicted | Human, Mouse, Rat, Rabbit, Chicken, Dog, Horse, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 65 kDa |
| Gene ID | 22955 |
|---|---|
| Alias Symbol | Scml3 |
| Other Names | Polycomb protein SCMH1, Sex comb on midleg homolog 1, SCMH1 {ECO:0000312|EMBL:CAH727931} |
| Target/Specificity | SCMH1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-SCMH1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | SCMH1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SCMH1 {ECO:0000312|EMBL:CAH72793.1} |
|---|---|
| Function | Associates with Polycomb group (PcG) multiprotein complexes; the complex class is required to maintain the transcriptionally repressive state of some genes. |
| Cellular Location | Nucleus. |
| Tissue Location | Strongly expressed in heart, muscle and pancreas. Weakly expressed in brain, placenta, lung, liver and kidney |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This is a rabbit polyclonal antibody against SCMH1. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).
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If you have any additional inquiries please email technical services at tech@abcepta.com.
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