|Other Accession||Q8IUM7, NP_849195, NM_178864|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse, Sheep, Bovine|
|Predicted||Human, Mouse, Rat, Rabbit, Pig, Dog, Horse, Bovine|
|Calculated MW||87 kDa|
|Alias Symbol||Le-PAS, NXF, PASD10, bHLHe79|
|Other Names||Neuronal PAS domain-containing protein 4, Neuronal PAS4, Class E basic helix-loop-helix protein 79, bHLHe79, HLH-PAS transcription factor NXF, PAS domain-containing protein 10, NPAS4, BHLHE79, NXF, PASD10|
|Target/Specificity||NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2, MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events.NXF is a member of the basic helix-loop-helix-PER (MIM 602260)-ARNT (MIM 126110)-SIM (see SIM2, MIM 600892) (bHLH-PAS) class of transcriptional regulators, which are involved in a wide range of physiologic and developmental events (Ooe et al., 2004 [PubMed 14701734]).[supplied by OMIM].|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-NPAS4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||NPAS4 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||BHLHE79, NXF, PASD10|
|Function||Acts as a transcriptional activator in the presence of ARNT. Can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene.|
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