WDHD1 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | O75717 |
Other Accession | O75717, NP_009017, NM_007086 |
Reactivity | Human, Mouse, Rat, Rabbit, Pig, Dog, Horse, Bovine |
Predicted | Human, Mouse, Rat, Rabbit, Pig, Chicken, Dog, Horse, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 126 kDa |
Gene ID | 11169 |
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Alias Symbol | AND-1, CTF4, CHTF4 |
Other Names | WD repeat and HMG-box DNA-binding protein 1, Acidic nucleoplasmic DNA-binding protein 1, And-1, WDHD1, AND1 |
Target/Specificity | Reactive with the SepB fragment (428-850aa) of WDHD1. WDHD1 contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. WDHD1 may also be involved in protein-protein interactions. The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-WDHD1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles. |
Precautions | WDHD1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | WDHD1 (HGNC:23170) |
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Synonyms | AND1 |
Function | Core replisome component that acts as a replication initiation factor. Binds directly to the CMG complex and functions as a hub to recruit additional proteins to the replication fork. |
Cellular Location | Nucleus, nucleoplasm |
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Provided below are standard protocols that you may find useful for product applications.
Background
This is a rabbit polyclonal antibody against WDHD1. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).
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