|Other Accession||Q9P1Z0, NP_065950, NM_020899|
|Reactivity||Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse|
|Predicted||Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse|
|Calculated MW||105 kDa|
|Alias Symbol||KAISO-L1, KIAA1538, ZNF903|
|Other Names||Zinc finger and BTB domain-containing protein 4, KAISO-like zinc finger protein 1, KAISO-L1, ZBTB4, KIAA1538|
|Target/Specificity||ZBTB4 may be involved in transcriptional regulation.|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-ZBTB4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ZBTB4 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional repressor with bimodal DNA-binding specificity. Represses transcription in a methyl-CpG-dependent manner. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Can also bind specifically to a single methyl-CpG pair and can bind hemimethylated DNA but with a lower affinity compared to methylated DNA (PubMed:16354688).|
|Cellular Location||Nucleus. Chromosome. Note=Localizes to chromocenters.|
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