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ZBTB4 antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - ZBTB4 antibody - middle region AI10082
    ZBTB4 antibody - middle region (AI10082) in Human Spleen cells using Western Blot
    WB Suggested Anti-ZBTB4 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: Human Spleen
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9P1Z0
Other Accession Q9P1Z0, NP_065950, NM_020899
Reactivity Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse
Predicted Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse
Host Rabbit
Clonality Polyclonal
Calculated MW 105 kDa
Additional Information
Gene ID 57659
Alias Symbol KAISO-L1, KIAA1538, ZNF903
Other Names Zinc finger and BTB domain-containing protein 4, KAISO-like zinc finger protein 1, KAISO-L1, ZBTB4, KIAA1538
Target/Specificity ZBTB4 may be involved in transcriptional regulation.
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-ZBTB4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsZBTB4 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZBTB4
Synonyms KIAA1538
Function Transcriptional repressor with bimodal DNA-binding specificity. Represses transcription in a methyl-CpG-dependent manner. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Can also bind specifically to a single methyl-CpG pair and can bind hemimethylated DNA but with a lower affinity compared to methylated DNA (PubMed:16354688). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self- renewal (By similarity).
Cellular Location Nucleus. Chromosome. Note=Localizes to chromocenters
Citations (0)
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Background

This is a rabbit polyclonal antibody against ZBTB4. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).

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$ 389.00
Cat# AI10082
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