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RUNX1T1 antibody - middle region

Rabbit Polyclonal Antibody

  • WB - RUNX1T1 antibody - middle region AI10108
    RUNX1T1 antibody - middle region (AI10108) in Human 721_B cells using Western Blot
    Host: Rabbit
    Target Name: WT1
    Sample Tissue: 721_B
    Antibody Dilution: 1.0μg/mlRUNX1T1 is supported by BioGPS gene expression data to be expressed in 721_B
  • WB - RUNX1T1 antibody - middle region AI10108
    RUNX1T1 antibody - middle region (AI10108) in Human HepG2 cells using Western Blot
    WB Suggested Anti-RUNX1T1 Antibody Titration: 1.25μg/ml
    Positive Control: HepG2 cell lysate
    There is BioGPS gene expression data showing that RUNX1T1 is expressed in HepG2
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q06455
Other Accession Q06455, NP_783554, NM_175636
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine
Predicted Human, Mouse, Rat, Zebrafish, Pig, Chicken, Dog, Horse
Host Rabbit
Clonality Polyclonal
Calculated MW 62 kDa
Additional Information
Gene ID 862
Alias Symbol CDR, ETO, MTG8, AML1T1, ZMYND2, CBFA2T1
Other Names Protein CBFA2T1, Cyclin-D-related protein, Eight twenty one protein, Protein ETO, Protein MTG8, Zinc finger MYND domain-containing protein 2, RUNX1T1, AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Target/Specificity RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8, 21)(q22, q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation.
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-RUNX1T1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRUNX1T1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RUNX1T1
Synonyms AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2
Function Transcription regulator that excerts its function by binding to histone deacetylases and transcription factors. Can repress transactivation mediated by TCF12.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00440, ECO:0000269|PubMed:10973986}. Note=Colocalizes with ATN1 in discrete nuclear dots
Tissue Location Most abundantly expressed in brain. Lower levels in lung, heart, testis and ovary
Research Areas
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This is a rabbit polyclonal antibody against RUNX1T1. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (

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$ 232.00
Cat# AI10108
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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