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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RIPX antibody - C-terminal region   

RIPX antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - RIPX antibody - C-terminal region AI10128
    RIPX antibody - C-terminal region (AI10128) in Human Jurkat cells using Western Blot
    WB Suggested Anti-RIPX Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:62500
    Positive Control: Jurkat cell lysate
    RUFY3 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q7L099
Other Accession Q7L099, NP_055776, NM_014961
Reactivity Human, Mouse, Rat, Rabbit, Pig, Dog, Guinea Pig, Horse, Bovine
Predicted Human, Mouse, Rat, Dog, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 53 kDa
Additional Information
Gene ID 22902
Alias Symbol RIPX, SINGAR1
Other Names Protein RUFY3, Rap2-interacting protein x, RIPx, Single axon-regulated protein, Singar, RUFY3, KIAA0871
Target/Specificity Located on chromosome 4, the RIPX encodes a protein with unknown function.
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-RIPX antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRIPX antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RUFY3 (HGNC:30285)
Synonyms KIAA0871
Function Plays a role in the generation of neuronal polarity formation and axon growth (By similarity). Implicated in the formation of a single axon by developing neurons (By similarity). May inhibit the formation of additional axons by inhibition of PI3K in minor neuronal processes (By similarity). Plays a role in the formation of F-actin-enriched protrusive structures at the cell periphery (PubMed:25766321). Plays a role in cytoskeletal organization by regulating the subcellular localization of FSCN1 and DBN1 at axonal growth cones (By similarity). Promotes gastric cancer cell migration and invasion in a PAK1-dependent manner (PubMed:25766321).
Cellular Location Cytoplasm. Endomembrane system. Cell projection, invadopodium. Perikaryon {ECO:0000250|UniProtKB:Q9D394}. Cell projection {ECO:0000250|UniProtKB:Q9D394}. Cell projection, growth cone {ECO:0000250|UniProtKB:Q9D394}. Cell projection, filopodium {ECO:0000250|UniProtKB:Q9D394}. Cell projection, lamellipodium {ECO:0000250|UniProtKB:Q9D394}. Note=Colocalizes with PAK1, F- actin, myosins and integrins in invadopodia at the cell periphery (PubMed:25766321). Colocalized with Ras-related Rab-5 proteins in cytoplasmic vesicles (PubMed:20376209). Accumulates in axon growth cones in a F-actin-dependent manner (By similarity). Colocalized with FSCN1 and F-actin at filipodia and lamellipodia of axonal growth cones (By similarity). Colocalized with DBN1 and F-actin at transitional domain of the axonal growth cone (By similarity) {ECO:0000250|UniProtKB:Q5FVJ0, ECO:0000250|UniProtKB:Q9D394, ECO:0000269|PubMed:20376209, ECO:0000269|PubMed:25766321}
Tissue Location Overexpressed in gastric cancer cells and tissues (at protein level) (PubMed:25766321)
Research Areas
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Background

This is a rabbit polyclonal antibody against RIPX. It was validated on Western Blot using a cell lysate as a positive control. Abgent strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (sales@abgent.com).

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$ 293.00
Cat# AI10128
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