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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Zebrafish   >   APG4B antibody - C-terminal region   

APG4B antibody - C-terminal region

Rabbit Polyclonal Antibody

  • IHC - APG4B antibody - C-terminal region AI10131
    APG4B antibody - C-terminal region (AI10131) in Human kidney cells using Immunohistochemistry
    Human kidney
  • IHC - APG4B antibody - C-terminal region AI10131
    Human Lung
    Rabbit Anti-ATG4B Antibody
    Paraffin Embedded Tissue: Human alveolar cell
    Cellular Data: Epithelial cells of renal tubule
    Antibody Concentration: 4.0-8.0 μg/ml
    Magnification: 400X
  • WB - APG4B antibody - C-terminal region AI10131
    APG4B antibody - C-terminal region (AI10131) in Human Raji cells using Western Blot
    WB Suggested Anti-APG4B Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:12500
    Positive Control: Raji cell lysate
    ATG4B is strongly supported by BioGPS gene expression data to be expressed in Human Raji cells
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y4P1
Other Accession Q9Y4P1, NP_037457, NM_013325
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine
Predicted Human, Mouse, Rat, Zebrafish, Pig, Chicken, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 44 kDa
Additional Information
Gene ID 23192
Alias Symbol APG4B, AUTL1
Other Names Cysteine protease ATG4B, 3422-, AUT-like 1 cysteine endopeptidase, Autophagin-1, Autophagy-related cysteine endopeptidase 1, Autophagy-related protein 4 homolog B, hAPG4B, ATG4B, APG4B, AUTL1, KIAA0943
Target/Specificity Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. APG4B encodes a member of the autophagin protein family and is also designated as a member of the C-54 family of cysteine proteases.
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-APG4B antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsAPG4B antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATG4B
Synonyms APG4B, AUTL1, KIAA0943
Function Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C- terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Cellular Location Cytoplasm.
Tissue Location Mainly expressed in the skeletal muscle, followed by brain, heart, liver and pancreas
Research Areas
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This is a rabbit polyclonal antibody against APG4B. It was validated on Western Blot and immunohistochemistry by Abgent. At Abgent we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high throughput manner. Our antibodies are peptide based and protein family oriented. We usually provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (

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$ 293.00
Cat# AI10131
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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