|Other Accession||Q9Y4W2, NP_112483, NM_031206|
|Reactivity||Human, Horse, Bovine|
|Predicted||Human, Horse, Bovine|
|Calculated MW||83 kDa|
|Alias Symbol||Las1-like, dJ475B7.2|
|Other Names||Ribosomal biogenesis protein LAS1L, Protein LAS1 homolog, LAS1L|
|Target/Specificity||The function of LAS1L has not been determined.|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-LAS1L antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||LAS1L Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the biogenesis of the 60S ribosomal subunit. Required for maturation of the 28S rRNA. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.|
|Cellular Location||Nucleus, nucleolus Nucleus, nucleoplasm. Cytoplasm Note=Mainly found in the nucleoplasm, with low levels detected in the cytoplasmic and chromatin fractions (By similarity). Localizes mainly to the granular component, the region implicated in the later steps of rRNA processing and subunit assembly and export|
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This is a rabbit polyclonal antibody against LAS1L. It was validated on Western Blot by Abgent. At Abgent we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high throughput manner. Our antibodies are peptide based and protein family oriented. We usually provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (firstname.lastname@example.org).
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