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CHRNB2 antibody - middle region

Rabbit Polyclonal Antibody

  • IHC - CHRNB2 antibody - middle region AI10149
    CHRNB2 antibody - middle region (AI10149) in Human kidney cells using Immunohistochemistry
    Human kidney
  • WB - CHRNB2 antibody - middle region AI10149
    CHRNB2 antibody - middle region (AI10149) in Human Jurkat cells using Western Blot
    WB Suggested Anti-CHRNB2 Antibody Titration: 2.5μg/ml
    Positive Control: Jurkat cell lysate
    CHRNB2 is supported by BioGPS gene expression data to be expressed in Jurkat
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P17787
Other Accession P17787, NP_000739, NM_000748
Reactivity Human, Mouse, Rat, Pig, Dog, Guinea Pig, Bovine
Predicted Human, Mouse, Pig, Dog, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 57 kDa
Additional Information
Gene ID 1141
Alias Symbol EFNL3, nAChRB2
Other Names Neuronal acetylcholine receptor subunit beta-2, CHRNB2
Target/Specificity Mutations in nAChRs are found in a rare form of nocturnal frontal lobe epilepsy . Previously, some nAChR mutations have been described that are associated with additional neurological features such as psychiatric disorders or cognitive defects. A new CHRNB2 mutation located in transmembrane region 3 (M3), outside the known ADNFLE mutation cluster. The CHRNB2 mutation I312M, which occurred de novo in twins, markedly increases the receptor's sensitivity to acetylcholine. Phenotypically, the mutation is associated not only with typical ADNFLE, but also with distinct deficits in memory. The cognitive problems are most obvious in tasks requiring the organization and storage of verbal information.
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-CHRNB2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsCHRNB2 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodiun ions.
Cellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Research Areas
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This is a rabbit polyclonal antibody against CHRNB2. It was validated on Western Blot and immunohistochemistry by Abgent. At Abgent we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high throughput manner. Our antibodies are peptide based and protein family oriented. We usually provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (

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$ 232.00
Cat# AI10149
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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