Atf3 Antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q60765 |
Other Accession | NM_007498, NP_031524 |
Reactivity | Human, Mouse, Rat, Zebrafish, Pig, Horse, Bovine, Dog |
Predicted | Human, Mouse, Rat, Zebrafish, Pig, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 21kDa |
Gene ID | 11910 |
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Alias Symbol | LRG-21 |
Other Names | Cyclic AMP-dependent transcription factor ATF-3, cAMP-dependent transcription factor ATF-3, Activating transcription factor 3, Transcription factor LRG-21, Atf3 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Atf3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Atf3 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Atf3 {ECO:0000303|PubMed:11916968, ECO:0000312|MGI:MGI:109384} |
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Function | This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters (PubMed:11916968). Represses transcription from promoters with ATF sites (PubMed:11916968). It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter (By similarity). |
Cellular Location | Nucleus {ECO:0000250|UniProtKB:P18847, ECO:0000255|PROSITE-ProRule:PRU00978} |
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