|Application ||WB, IHC|
|Other Accession||NM_002505, NP_002496|
|Reactivity||Human, Mouse, Rat, Pig, Horse, Yeast, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Pig, Chicken, Bovine, Guinea Pig, Dog|
|Alias Symbol||HAP2, CBF-A, CBF-B, NF-YA|
|Other Names||Nuclear transcription factor Y subunit alpha, CAAT box DNA-binding protein subunit A, Nuclear transcription factor Y subunit A, NF-YA, NFYA|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 100 ul of distilled water. Final anti-NFYA antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||NFYA antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'- CCAAT-3' box motif found in the promoters of its target genes. NF- Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component ARNTL/BMAL1.|
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Provided below are standard protocols that you may find useful for product applications.
Zhu,Q.S.,et al.,(2004) J.Biol.Chem.279(29):29902-29910Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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