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> home > Products > Primary Antibodies > Antibody Collections > Zebrafish > Avil antibody - N-terminal region
Avil antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
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- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9WU06 |
| Other Accession | NM_024401, NP_077377 |
| Reactivity | Human, Mouse, Rat, Zebrafish, Horse, Bovine, Dog |
| Predicted | Human, Mouse, Rat, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 91kDa |
| Gene ID | 79253 |
|---|---|
| Other Names | Advillin, Peripheral nervous system villin-like protein, Pervin, Avil, Advil |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Avil antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | Avil antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | Avil {ECO:0000312|RGD:620301} |
|---|---|
| Function | Ca(2+)-regulated actin-binding protein which plays an important role in actin bundling. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1- mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates (PubMed:11849295). Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis. In podocytes, controls lamellipodia formation through the regulation of EGF-induced diacylglycerol generation by PLCE1 and ARP2/3 complex assembly (By similarity). |
| Cellular Location | Cytoplasm, cytoskeleton. Cell projection, neuron projection. Cell projection, axon. Cell projection, lamellipodium {ECO:0000250|UniProtKB:O75366}. Cell junction, focal adhesion {ECO:0000250|UniProtKB:O75366}. Note=In podocytes, present in the F- actin-enriched cell periphery that generates lamellipodia and focal adhesions. {ECO:0000250|UniProtKB:O75366} |
| Tissue Location | Expressed in dorsal root ganglion (DRG) neurons and superior cervical ganglia (SCG) (PubMed:11849295). Expressed in podocytes (PubMed:29058690). |
Research Areas
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$ 389.00
Cat# AI10235
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