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SLC26A3 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P40879 |
| Other Accession | NM_000111, NP_000102 |
| Reactivity | Human, Mouse, Rat, Pig, Sheep, Bovine, Dog |
| Predicted | Human, Mouse, Pig, Sheep, Bovine, Guinea Pig, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 84kDa |
| Gene ID | 1811 |
|---|---|
| Alias Symbol | CLD, DRA |
| Other Names | Chloride anion exchanger, Down-regulated in adenoma, Protein DRA, Solute carrier family 26 member 3, SLC26A3, DRA |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-SLC26A3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | SLC26A3 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SLC26A3 |
|---|---|
| Synonyms | DRA |
| Function | Mediates chloride-bicarbonate exchange with a chloride bicarbonate stoichiometry of 2:1 in the intestinal epithelia (PubMed:16606687, PubMed:19321737, PubMed:22159084, PubMed:22627094). Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation (By similarity). |
| Cellular Location | Apical cell membrane; Multi-pass membrane protein. Membrane {ECO:0000250|UniProtKB:Q9WVC8}; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Localized in sperm membranes Midpiece of sperm tail. Colocalizes with CFTR at the midpiece of sperm tail (By similarity). {ECO:0000250|UniProtKB:Q9WVC8} |
| Tissue Location | Expressed in the colon. Expression is significantly decreased in adenomas (polyps) and adenocarcinomas of the colon |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Dorwart,M.R., (2008) J. Biol. Chem. 283 (13), 8711-8722 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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