Wnt2 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P21552 |
Other Accession | NM_023653, NP_076142 |
Reactivity | Human, Mouse, Rat, Zebrafish, Pig, Sheep, Horse, Bovine, Dog |
Predicted | Human, Mouse, Rat, Zebrafish, Pig, Bovine, Guinea Pig, Dog |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 40kDa |
Gene ID | 22413 |
---|---|
Alias Symbol | 2610510E18Rik, Int1l1, Irp, Mirp, Wnt-2, Wnt2a |
Other Names | Protein Wnt-2, INT-1-related protein, IRP, Wnt2, Irp, Wnt-2 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Wnt2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Wnt2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Wnt2 |
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Synonyms | Irp, Wnt-2 |
Function | Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt/beta-catenin signaling pathway (PubMed:19686689). Functions as a upstream regulator of FGF10 expression (PubMed:19686689). Plays an important role in embryonic lung development (PubMed:19686689). May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (PubMed:20018874). |
Cellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:P09544}. Secreted {ECO:0000250|UniProtKB:P09544} |
Tissue Location | In embryos in the developing allantois, pericardium heart, and ventral-lateral mesoderm; in adults in lung, brain, heart and placenta |
Provided below are standard protocols that you may find useful for product applications.
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