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KIN antibody - middle region

Rabbit Polyclonal Antibody

  • WB - KIN antibody - middle region AI10340
    WB Suggested Anti-KIN Antibody Titration: 2.5μg/ml
    Positive Control: Jurkat cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60870
Other Accession NM_012311, NP_036443
Reactivity Human, Mouse, Rat, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Chicken, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 45kDa
Additional Information
Gene ID 22944
Alias Symbol BTCD, KIN17
Other Names DNA/RNA-binding protein KIN17, Binding to curved DNA, KIN, antigenic determinant of recA protein homolog, KIN (HGNC:6327), BTCD, KIN17
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-KIN antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsKIN antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KIN (HGNC:6327)
Synonyms BTCD, KIN17
Function Involved in DNA replication and the cellular response to DNA damage. May participate in DNA replication factories and create a bridge between DNA replication and repair mediated by high molecular weight complexes. May play a role in illegitimate recombination and regulation of gene expression. May participate in mRNA processing. Binds, in vitro, to double-stranded DNA. Also shown to bind preferentially to curved DNA in vitro and in vivo (By similarity). Binds via its C-terminal domain to RNA in vitro.
Cellular Location Nucleus Cytoplasm Note=During S phase, strongly associated with the nuclear matrix, and to chromosomal DNA in the presence of DNA damage. Also shows cytoplasmic localization in elongated spermatids {ECO:0000250|UniProtKB:Q8K339, ECO:0000269|PubMed:11880372, ECO:0000269|PubMed:12359749, ECO:0000269|PubMed:12754299, ECO:0000269|PubMed:12853634, ECO:0000269|PubMed:15831485}
Tissue Location Ubiquitously expressed in all tissues examined, with highest levels in skeletal muscle, heart and testis. Differentially expressed in non-tumorigenic and tumorigenic cell lines. Highly expressed in proliferating epithelial keratinocyte cells in vitro (at protein level)
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le Acta Crystallograph. Sect. F Struct. Biol. Cryst. Commun. 62 (PTReconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 232.00
Cat# AI10340
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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