|Other Accession||NM_010347, NP_034477|
|Reactivity||Human, Mouse, Rat, Bovine|
|Predicted||Human, Mouse, Rat, Pig, Bovine, Guinea Pig|
|Alias Symbol||AL024115, Grg, Grg5|
|Other Names||Amino-terminal enhancer of split, Amino enhancer of split, Grg-5, Groucho-related protein 5, Protein ESP1, Protein GRG, Aes, Esp1, Grg, Grg5|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Aes antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Aes Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||Esp1, Grg, Grg5|
|Function||Transcriptional corepressor. Acts as dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development.|
|Tissue Location||Ubiquitously expressed in developing embryos by midgestation, a wide expression is conserved in adult. In mouse, abundantly expressed in muscle, heart and brain|
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