Aes Antibody - N-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | P63002 |
Other Accession | NM_010347, NP_034477 |
Reactivity | Human, Mouse, Rat, Bovine |
Predicted | Human, Mouse, Rat, Pig, Bovine, Guinea Pig |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 22kDa |
Gene ID | 14797 |
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Alias Symbol | AL024115, Grg, Grg5 |
Other Names | Amino-terminal enhancer of split, Amino enhancer of split, Grg-5, Groucho-related protein 5, Protein ESP1, Protein GRG, Aes, Esp1, Grg, Grg5 |
Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Reconstitution & Storage | Add 50 ul of distilled water. Final anti-Aes antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
Precautions | Aes Antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | Tle5 {ECO:0000305} |
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Function | Transcriptional corepressor. Acts as a dominant repressor towards other family members. Inhibits NF-kappa-B-regulated gene expression. May be required for the initiation and maintenance of the differentiated state. Essential for the transcriptional repressor activity of SIX3 during retina and lens development. |
Cellular Location | Nucleus. |
Tissue Location | Ubiquitously expressed in developing embryos by midgestation, a wide expression is conserved in adult. In mouse, abundantly expressed in muscle, heart and brain |
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