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LHX3 antibody - middle region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | Q9UBR4 |
| Other Accession | NM_178138, NP_835258 |
| Reactivity | Human, Mouse, Rat, Zebrafish, Pig, Horse, Bovine, Dog |
| Predicted | Human, Mouse, Rat, Zebrafish, Pig, Chicken, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 43kDa |
| Gene ID | 8022 |
|---|---|
| Alias Symbol | DKFZp762A2013, M2-LHX3, LIM3, CPHD3 |
| Other Names | LIM/homeobox protein Lhx3, LIM homeobox protein 3, LHX3 |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-LHX3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | LHX3 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | LHX3 |
|---|---|
| Function | Transcription factor. Recognizes and binds to the consensus sequence motif 5'-AATTAATTA-3' in the regulatory elements of target genes, such as glycoprotein hormones alpha chain CGA and visual system homeobox CHX10, positively modulating transcription; transcription can be co-activated by LDB2. Synergistically enhances transcription from the prolactin promoter in cooperation with POU1F1/Pit-1 (By similarity). Required for the establishment of the specialized cells of the pituitary gland and the nervous system (PubMed:21149718). Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1 (By similarity). |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
References
Yaden,B.C., et al., (2006) Endocrinology 147 (1), 324-337Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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