|Other Accession||NM_015251, NP_056066|
|Reactivity||Human, Mouse, Rat, Horse, Bovine, Dog|
|Predicted||Human, Mouse, Rat, Bovine, Dog|
|Alias Symbol||ASCIZ, DKFZp779K1455, FLJ76795, KIAA0431, znf822, ZNF822|
|Other Names||ATM interactor, ATM/ATR-substrate CHK2-interacting zinc finger protein, ASCIZ, Zinc finger protein 822, ATMIN, KIAA0431, ZNF822|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-ATMIN antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ATMIN antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor. Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM. Binds to the DYNLL1 promoter and activates its transcription.|
|Cellular Location||Nucleus. Note=Nuclear, in discrete foci during G1 phase|
|Tissue Location||Ubiquitously expressed in normal tissues and cancer cell lines with highest levels in placenta and skeletal muscle.|
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Provided below are standard protocols that you may find useful for product applications.
Oka,H., (2008) Biochem. Biophys. Res. Commun. 371 (2), 225-229 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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