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Smad6 Antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - Smad6 Antibody - C-terminal region AI10402

    Target Name:Smad6
    Sample Tissue: Mouse Kidney lysates
    Antibody Dilution:1.μg/ml

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O35182
Reactivity Human, Mouse, Rat, Zebrafish, Pig, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Zebrafish, Pig, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 54kDa
Additional Information
Gene ID 17130
Other Names Mothers against decapentaplegic homolog 6, MAD homolog 6, Mothers against DPP homolog 6, Mad homolog 7, SMAD family member 6, SMAD 6, Smad6, Smad6, Madh6, Madh7, Msmad6
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 &mu, l of distilled water. Final Anti-Smad6 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsSmad6 Antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Smad6
Synonyms Madh6, Madh7, Msmad6
Function Binds to regulatory elements in target promoter regions (By similarity). May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding (By similarity). Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes.
Cellular Location Nucleus.
Tissue Location Ubiquitous in various organs, with higher levels in lung
Research Areas
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$ 293.00
Cat# AI10402
(40 western blots)
Availability: 2-3 days
Bulk Size
Seasonal Special on Bulk Order
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