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NR4A2 antibody - C-terminal region
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P43354 |
| Other Accession | NM_006186, NP_006177 |
| Reactivity | Human, Mouse, Rat, Zebrafish, Pig, Horse, Bovine, Dog |
| Predicted | Human, Mouse, Rat, Zebrafish, Pig, Chicken, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 66kDa |
| Gene ID | 4929 |
|---|---|
| Alias Symbol | HZF-3, NOT, NURR1, RNR1, TINUR |
| Other Names | Nuclear receptor subfamily 4 group A member 2, Immediate-early response protein NOT, Orphan nuclear receptor NURR1, Transcriptionally-inducible nuclear receptor, NR4A2, NOT, NURR1, TINUR |
| Format | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
| Reconstitution & Storage | Add 50 ul of distilled water. Final anti-NR4A2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles. |
| Precautions | NR4A2 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NR4A2 |
|---|---|
| Synonyms | NOT, NURR1, TINUR |
| Function | Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development (PubMed:17184956, PubMed:15716272). It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons (By similarity). |
| Cellular Location | Cytoplasm. Nucleus. Note=Mostly nuclear; oxidative stress promotes cytoplasmic localization |
| Tissue Location | Expressed in a number of cell lines of T-cell, B- cell and fibroblast origin. Strong expression in brain tissue |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Holla,V.R., (2006) J. Biol. Chem. 281 (5), 2676-2682 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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