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Hes6 Antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - Hes6 Antibody - middle region AI10435
    WB Suggested Anti-Hes6 Antibody
    Titration: 1. μg/ml
    Positive Control: Mouse Stomach
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q9JHE6
Other Accession NM_019479, NP_062352
Reactivity Human, Mouse, Rat, Zebrafish, Pig, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Zebrafish, Pig, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 24kDa
Additional Information
Gene ID 55927
Alias Symbol AI326893, bHLHb41
Other Names Transcription cofactor HES-6, Hairy and enhancer of split 6, Hes6 {ECO:0000312|EMBL:BAA96081.1}
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Hes6 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsHes6 Antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Hes6 {ECO:0000312|EMBL:BAA96081.1}
Function Does not bind DNA itself but suppresses both HES1-mediated N box-dependent transcriptional repression and binding of HES1 to E box sequences. Also suppresses HES1-mediated inhibition of the heterodimer formed by ASCL1/MASH1 and TCF3/E47, allowing ASCL1 and TCF3 to up- regulate transcription in its presence. Promotes cell differentiation.
Cellular Location Nucleus.
Tissue Location Expressed in both undifferentiated and differentiated cells. High levels of expression are observed in several embryonic tissues including the nervous system, muscle and thymus. In the nervous system, initially expressed in the closing neural tube, then in the spinal cord, cranial and dorsal root ganglia, and brain neuroepithelium. Also expressed in epithelial cells of the embryonic respiratory, urinary and digestive systems. In the limb buds, expressed in skeletal muscle and presumptive tendons
Research Areas
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$ 389.00
Cat# AI10435
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